2025

TYPE-1 NNOS NEURONS ORCHESTRATE CORTICAL NEURAL ACTIVITY AND VASOMOTION

BioRXiv

Turner, Brockway, Hossain, Griffith, Greenawalt, Zhang, Gheres, Crowley, & Drew

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2024

ALCOHOL CONSUMPTION CONFERS LASTING IMPACTS ON PREFRONTAL CORTICAL NEURON INTRINSIC EXCITABILITY AND SPONTANEOUS NEUROTRANSMITTER SIGNALIGN IN THE AGING BRAIN IN MICE

Neurobiology of Aging

Smith, Griffith, Sicher, Brockway, Proctor, & Crowley​

 

VOLUNTARY ADOLESCENT ALCOHOL EXPOSURE DOES NOT INCREASE ADULTHOOD CONSUMPTION OF ALCOHOL IN MULTIPLE MOUSE AND RAT MODELS

Addiction Neuroscience

Sicher, Liss, Vozella, Marsland, Seemiller, Springer, Starnes, Griffith, Smith, Astefanous, Deak, Roberto, Varodayan, & Crowley

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EMERGING PHARMACOLOGICAL TARGETS FOR ALCOHOL USE DISORDER

Alcohol 

Brockway & Crowley​

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ALCOHOL AND STRESS EXPOSURE ACROSS THE LIFESPAN ARE KEY RISK FACTORS FOR ALZHEIMER'S DISEASE AND COGNITIVE DECLINE
Neurobiology of Stress (PDF here)
Seemiller,  Flores Cuadra, Griffith, Smith, & Crowley

 

2023
SOMATOSTATIN PEPTIDE SIGNALING DAMPENS CORTICAL CIRCUITS AND PROMOTES EXPLORATORY BEHAVIOR
Cell Reports (PDF here)
(code and data)
Brockway, Moyer, Aloimonos, Clarity, Griffith, Smith, Dao, Hossain, Drew, Gordon, Kupferschmidt, & Crowley

ADOLESCENT BINGE DRINKING LEADS TO LONG-LASTING CHANGES IN CORTICAL MICROCIRCUITS IN MICE
Neuropharmacology (PDF here)
Sicher, Starnes, Griffith, Dao, Smith, Brockway, & Crowley
 

2022 
PREDICTIVE LINK BETWEEN SYSTEMIC METABOLISM AND CYTOKINE SIGNATURES IN THE BRAIN OF APOLIPOPROTEIN E E4 MICE
Neurobiology of Aging (PDF here)
Fleeman, Snyder, Kuhn, Chan, Smith, Crowley, Arnold, & Proctor

AN INNOVATIVE APPROACH TO EXAMINING THEROLE OF NEUROTRANSMITTERS IN FEAR CIRCUITS
Neuropsychopharmacology  (PDF here)
Griffith & Crowley

TARGETED AND TRANSIENT OPENING OF THE BLOOD BRAIN BARRIER IN DISCRETE NEUROCIRCUITS AND BRAIN REGIONS
Neuropsychopharmacology (PDF here) 
Crowley & Medina

SOMATOSTATIN NEURONS IN THE BED NUCLEUS OF THE STRIA TERMINALIS PLAY A SEX-DEPENDENT ROLE IN BINGE DRINKING
Brain Research Bulletin (PDF here)
Suresh Nair, Dao, Lopez Melean, Griffith, Starnes, Moyer, Sicher, Brockway, Meeks, & Crowley

ADOLESCENT ALCOHOL AND STRESS EXPOSURE REWIRES KEY CORITCAL NEUROCIRCUITRY
Frontiers in Neuroscience (PDF here) 
Sicher, Duerr, Starnes, & Crowley
 

2021                                                                                           

DEVELOPING BREAKTHROUGH PSYCHIATRIC TREATMENTS BY MODULATING G-PROTEIN COUPLED RECEPTORS ON PREFRONTAL CORTEX SOMATOSTATIN NEURONS
Neuropsychopharmacology  (PDF here)
Crowley & Joffe     

SOMATOSTATIN NEURONS CONTROL AN ALCOHOL BINGE DRINKING PRELIMBIC MICROCIRCUIT IN MICE
Neuropsychopharmacology (PDF here) 
Dao, Brockway, Suresh Nair, Sicher, & Crowley
WINNER OF THE 2022 ACNP NEECA AWARD

 

2020 

FULL FUNCTION OF EXON JUNCTION COMPLEX FACTOR RBM8A IS CRITICAL FOR INTERNEURON DEVELOPMENT

Translational Psychiatry 

McSweeney, Dong, Chen, Vitale, Xu, Crowley, Luscher, Zou, & Mao

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TURNING THE 'TIDES ON NEUROPSYCHIATRIC DISEASES: THE ROLE OF PEPTIDES IN THE PREFRONTAL CORTEX

Frontiers in Behavioral Neuroscience 

Brockway, & Crowley

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FORCED ABSTINENCE FROM ALCOHOL INDUCES SEX-SPECIFIC DEPRESSION-LIKE BEHAVIOR AND NEURAL ADAPTATIONS IN SOMATOSTATIN NEURONS IN CORTICAL AND AMYGDALAR REGIONS

Frontiers in Behavioral Neuroscience 

Dao, Nair, Magee, Moyer, Sendao, Brockway, & Crowley

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MANIPULATION OF CENTRAL AMYGDALA NEUROTENSIN NEURONS ALTERS ALCOHOL CONSUMPTION

The Journal of Neuroscience 

Torruelle-Suarez, Vandenberg, Tipton, Luster, Dange, Patel, McHenry, Hardaway, Kantak, Crowley,   DiBerto, Faccidomo, Hodge, Stuber, & McElligott

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2019       

ANIMAL MODELS OF ALCOHOL USE DISORDER AND THE BRAIN: FROM CASUAL DRINKING TO DEPENDENCE

Translational Issues in Psychological Science 

Crowley, Dao, Magee, Bourcier, & Lowery-Gionta

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IN VITRO OPTOGENETIC CHARACTERIZATION OF NEUROPEPTIDE RELEASE FROM PREFRONTAL CORTICAL SOMATOSTATIN NEURONS

Neuroscience 

Dao, Brockway, & Crowley

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REVERSAL OF A TREATMENT-RESISTANT, DEPRESSION-RLEATED BRAIN STATE WITH THE KV7 CHANNEL OPENER RETIGABINE

Neuroscience 

Feng, Crowley, Patel, Guo, Bugni, & Luscher

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KETAMINE NORMALIZES BINGE DRINKING-INDUCED DEFECTS IN GLUTAMATERGIC SYNAPTIC TRANSMISSION AND ETHANOL DRINKING BEHAVIOR IN FEMALE BUT NOT MALE MICE.

Neuropharmacology 

Crowley, Magee, Feng, Jefferson, Morris, Dao, Brockway, & Luscher

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 2018

CHRONIC STRESS DYSREGULATES AMYGDALAR OUTPUT TO THE PREFRONTAL CORTEX

Neuropharmacology 

Lowery-Gionta*, Crowley*, Bukalo*, Silverstein, Holmes, & Kash *co-first authorship

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ADOLESCENT SOCIAL STRESS INCREASES ANXIETY-LIKE BEHAVIOR AND ALTERS SYNAPTIC TRANSMISSION, WITHOUT INFLUENCING NICOTINE RESPONSES, IN A SEX-DEPENDENT MANNER

Neuroscience

Caruso, Crowley, Reiss, Caulfield, Luscher, Cavigelli, & Kamens

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2016                  

DYNORPHIN CONTROLS THE GAIN OF AN AMYGDALAR ANXIETY CIRCUIT

Cell Reports

Crowley, Bloodgood, Hardaway, Kendra, McCall, Al-Hasani, McCall, Yu, Schools, Krashes, Lowell, Whistler, Bruchas, & Kash

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2015

KAPPA OPIOID RECEPTOR SIGNALING THROUGHOUT THE BRAIN: INVOLVED CIRCUITRY AND IMPLICATIONS FOR TREATMENT

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Crowley & Kash

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INTEGRATED CIRCUITS AND MOLECULAR COMPONENTS FOR STRESS AND FEEDING: IMPLICATIONS FOR EATING DISORDERS

Genes, Brains, and Behavior

Hardaway*, Crowley*, Bulik, & Kash*co-first authorship

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DISTINCT SUBPOPULATIONS OF NUCLEUS ACCUMBENS DYNORPHIN NEURONS DRIVE AVERSION AND REWARD.

Neuron

Al-Hasani, McCall, Shin, Gomez, Schmitz, Bernardi, Pyo, Park, Marcinkiewcz, Crowley, Krashes, Lowell, Kash, Rogers, & Bruchas

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A DREADD FOR MULTIPLEXING CHEMOGENETIC INTERROGATION OF NEURAL CIRCUITS

Neuron

Vardy, Robinson, Li, Olsen, DiBerto, Sassano, Huang, Zhu, Urban, Rittiner, Crowley, Pleil, Song, Kash, Malanga, Krashes, & Roth

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EFFECTS OF CHRONIC ETHANOL EXPOSURE ON NEURONAL FUNCTION IN DISCRETE REGIONS OF THE PREFRONTAL CORTEX AND EXTENDED AMYGDALA

Neuropharmacology

Pleil, Lowery-Gionta, Crowley, Li, Marcinkiewcz, McCall, Maldonado-Devincci, Morrow, & Kash

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CHRONIC ALCOHOL ALTERS REWARDED BEHAVIORS AND STRIATAL PLASTICITY

Addiction Biology

Depoy, Daut, Wright, Camp, Crowley, Noronha, ... & Holmes

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2014                

CHRONIC METHYLPHENIDATE EXPOSURE DURING ADOLESCENCE REDUCES STRIATAL SYNAPTIC RESPONSES TO ETHANOL

European Journal of Neuroscience

Crowley, Cody, Davis, Lovinger, & Mateo

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NEUROPEPTIDE REGULATION OF SIGNALING AND BEHAVIOR IN THE BNST

Molecules and Cells

Kash, Pleil, Marcinkiewcz, Lowery-Gionta, Crowley, Mazzone, & McElligott

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GLUTAMATERGIC MECHANISMS ASSOCIATED WITH STRESS-INDUCED AMYGDALA EXCITABILITY AND ANXIETY-RELATED BEHAVIOR

Neuropharmacology

Masneuf, Lowery-Gionta, Colacicco, Pleil, Li, Crowley... Kash

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LRRK2 REGULATES SYNAPTOGENESIS AND DOPAMINE RECEPTOR ACTIVATION OF STRIATAL PROJECTION NEURONS THROUGH MODULATION OF PKA ACTIVITY

Nature Neuroscience

Parisiadou, Yu, Sgobio, Zie, Lui, Sun, Gu, Lin, Crowley, Lovinger & Cai

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CHRONIC ALCOHOL PRODUCES NEUROADAPTATIONS TO PRIME STRIATAL LEARNING

Proceedings of the National Academy of Sciences

DePoy, Daunt, Brigman, MacPherson, Crowley, Gunduz-Cinar, Pickens, Cinar, Saksida, Kunos, Lovinger, Bussey, Camp, & Holmes

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2011  

SEROTONIN INDUCES LONG-TERM DEPRESSION AT CORTICOSTRIATAL SYNAPSES

The Journal of Neuroscience 

Mathur, Capik [Crowley maiden name], Alvarez, & Lovinger